They'll get the chance to avenge their latest loss in a matchup this week with the 49ers, who continue to be one of the least healthy teams in the league with another member of the defensive line lost for the season in Mykel Williams.

Let's update our NFL Power Rankings ahead of Week 10. Plus, we picked out critical games remaining on the schedule for every team.

Leading the way on the waiver wire this week, a pair of tight ends who haven't made a huge impact so far this season but have golden opportunities.

Of the top 10 fantasy defenses on the season, perhaps the only one that wasn’t drafted regularly was the Patriots or the Seahawks; however, both were scooped up early on waivers and have a past history of success.

See the top projected fantasy players for Week 10. Our rankings highlight the best players to start in your fantasy football lineup.

Pete Prisco's Week 10 NFL Power Rankings

Palmer injured his ankle and knee early in the second quarter of the team’s Week 6 loss to the Falcons. He did not return to the game and was labeled as “ week-to-week ” by head coach Sean McDermott. He did not play in Week 8 or 9.

Week 10 of the FCS season was filled with Top 25 upsets. Within those upsets, there were a number of great performances for draft-eligible prospects. This week is highlighted by players from teams not in the top tier in the FCS, but they found a way to deliver great games for their respective programs.

See the top projected fantasy wide receivers for Week 10. Our rankings highlight the best WR options to start in your fantasy football lineup.

Colin Cowherd lists his top 10 teams in the NFL entering Week 10 of the 2025/26 NFL season.