Genetic differences that contribute to how long a person will live and their risk of Alzheimer's disease have been identified ...

Mutations in NPC1 cause Niemann-Pick Type C. Mice lacking NPC1 only in microglia have rampant neuroinflammation and impaired ...

Microglia can partially break down amyloid plaques by "spitting" a digestive enzyme at them, a new study has found.

Microglia have been revealed to first help spread Alzheimer’s disease pathology across the brain and then activate to limit ...

Researchers have discovered a link between a chronic gut infection caused by a common virus and the development of ...

A chronic gut infection caused by a common virus may be linked to the progression of Alzheimer ’s disease, a new study has ...

Owl Therapeutics ("Owl"), a biopharmaceutical company developing drugs to supercharge microglia, the immune cells of the ...

On track to report data from Phase 1 clinical trial evaluating VG-3927 for the treatment of Alzheimer’s disease in 1Q 2025 –– Final analysis ...

Discover how stressed-out immune cells in the brain may be the key culprit behind the development of Alzheimer's disease.

A sequence of stress signals among specialized clean-up cells in the brain could at last reveal why some immune responses can ...

Tiziana Life Sciences, Ltd. (Nasdaq: TLSA) (“Tiziana” or the “Company”), a biotechnology company developing breakthrough immunomodulation therapies with its lead development candidate, intranasal ...

This study describes a valuable new model for in vivo manipulation of microglia, exploring how mutations in the Adar1 gene within microglia contribute to Aicardi-Goutières Syndome. The methodology is ...