Mutations in NPC1 cause Niemann-Pick Type C. Mice lacking NPC1 only in microglia have rampant neuroinflammation and impaired ...

Genetic differences that contribute to how long a person will live and their risk of Alzheimer's disease have been identified ...

Microglia can partially break down amyloid plaques by "spitting" a digestive enzyme at them, a new study has found.

A study led by Turkish researcher Pinar Ayata unveiled a critical mechanism involving microglia—specialized immune cells in ...

Immune cells in the brain called microglia can partially break down large amyloid plaques characteristic of Alzheimer's ...

Researchers have discovered a link between a chronic gut infection caused by a common virus and the development of ...

Microglia have been revealed to first help spread Alzheimer’s disease pathology across the brain and then activate to limit ...

On track to report data from Phase 1 clinical trial evaluating VG-3927 for the treatment of Alzheimer’s disease in 1Q 2025 –– Final analysis ...

Tiziana Life Sciences, Ltd. (Nasdaq: TLSA) (“Tiziana” or the “Company”), a biotechnology company developing breakthrough immunomodulation therapies with its lead development candidate, intranasal ...

A sequence of stress signals among specialized clean-up cells in the brain could at last reveal why some immune responses can ...

This study describes a valuable new model for in vivo manipulation of microglia, exploring how mutations in the Adar1 gene within microglia contribute to Aicardi-Goutières Syndome. The methodology is ...