Seattle Seahawks vs Arizona Cardinals picks, predictions, odds: Who wins NFL Week 4 game?

NFL Week 4 odds, picks, predictions, TV channel, streaming information for Thursday Night Football game between Seattle Seahawks, Arizona Cardinals.

Jonathan Gannon hints at offensive changes after Arizona Cardinals' latest loss

The Arizona Cardinals offense has struggled through four weeks. Head coach Jonathan Gannon suggested that tweaks could be coming after their mini-bye.

3 Overreactions to Cardinals Loss vs Seahawks

Sep 25, 2025; Glendale, Arizona, USA; Arizona Cardinals running back Emari Demercado (31) celebrates with wide receiver Marvin Harrison Jr. (18) after scoring a touchdown against the Seattle Seahawks in the fourth quarter at State Farm Stadium. Mandatory Credit: Mark J. Rebilas-Imagn Images / Mark J. Rebilas-Imagn Images

Overreactions from Seahawks win over Cardinals: Kickoff penalty too severe? Kyler Murray peaked in Arizona?

Seattle avoided a major collapse once Jason Myers drilled a 52-yard field goal with no time left in regulation to escape the desert with a 23-20 victory, moving to 3-1 on the season and staying in position to compete for the division title. Despite the late rally, the Cardinals fall to 2-2 after winning their first two games to start the year.

What channel is Cardinals vs Seahawks game on TV tonight? TNF start time, NFL schedule, streaming

NFL Week 4 begins with the Arizona Cardinals hosting the Seattle Seahawks on Thursday Night Football tonight. Start time, schedule and how to watch.
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